Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569983 | 0.94 | DNM1 (0.40) | DNM1ALDH1A1CNR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7583332 | 0.91 | DNM1 (0.39) | DNM1ALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL4578889 | 0.81 | DNM1 (0.46) | DNM1ALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL12565683 | 0.80 | MEN1 (0.39) | DNM1ALDH1A1CNR1MEN1KMT2A | |
| SCHEMBL22382538 | 0.78 | DNM1 (0.36) | DNM1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL1827225 | 0.78 | MEN1 (0.54) | DNM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8741153 | 0.78 | MEN1 (0.48) | DNM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20710636 | 0.77 | DNM1 (0.59) | DNM1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20411687 | 0.77 | ECE1 (0.52) | DNM1CNR1KDM4EFAAHCNR2 | |
| SCHEMBL20414885 | 0.77 | ECE1 (0.52) | DNM1CNR1KDM4EFAAHCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |