SCHEMBL1827225

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1828419	0.98	MEN1 (0.52)	MEN1KMT2AALDH1A1SMN1; SMN2DNM1
	SCHEMBL1826928	0.98	MEN1 (0.52)	MEN1KMT2AALDH1A1SMN1; SMN2DNM1
	SCHEMBL8741153	0.95	MEN1 (0.48)	MEN1KMT2AALDH1A1SMN1; SMN2DNM1
	SCHEMBL5353889	0.89	CASP2 (0.62)	MEN1KMT2ADNM1CASP2NAAA
	SCHEMBL18402599	0.89	CASP2 (0.62)	MEN1KMT2ADNM1CASP2NAAA
	SCHEMBL31620140	0.89	CASP2 (0.62)	MEN1KMT2ADNM1CASP2NAAA
	SCHEMBL18871729	0.89	CASP2 (0.62)	MEN1KMT2ADNM1CASP2NAAA
	SCHEMBL31620138	0.89	CASP2 (0.62)	MEN1KMT2ADNM1CASP2NAAA
	SCHEMBL8956457	0.89	HDAC1 (0.49)	MEN1KMT2AALDH1A1SMN1; SMN2DNM1
	SCHEMBL29312927	0.89	CASP2 (0.62)	MEN1KMT2ADNM1CASP2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.