Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795132 | 1.00 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL9795126 | 1.00 | ALOX15 (0.57) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL9795327 | 0.98 | ALOX15 (0.56) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL9795181 | 0.98 | ALOX15 (0.56) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL9795189 | 0.98 | ALOX15 (0.56) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL13661582 | 0.91 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL19849339 | 0.86 | ALOX15 (0.59) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL8488134 | 0.84 | ALOX15 (0.54) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| SCHEMBL12820428 | 0.83 | ALOX15 (0.53) | ALOX15ALDH1A1SMN1; SMN2TSHRRECQL | |
| Oxalic Acid SCHEMBL9795524 | 0.82 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TSHRL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |