Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011698 | 0.84 | MEN1 (0.49) | HPGDALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL2009659 | 0.79 | MEN1 (0.51) | HPGDALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL9795292 | 0.78 | TSHR (0.39) | TSHRHPGDMEN1KMT2ABCHE | |
| SCHEMBL20113578 | 0.78 | KMT2A (0.54) | HPGDALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL13396780 | 0.77 | CNR1 (0.43) | TSHRHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL9795223 | 0.76 | TSHR (0.40) | TSHRHPGDMEN1KMT2ABCHE | |
| SCHEMBL13396698 | 0.76 | ECE1 (0.42) | TSHRHPGDEPHX2MEN1KMT2A | |
| SCHEMBL20104903 | 0.76 | HPGD (0.49) | TSHRHPGDALDH1A1FAAHSMN1; SMN2 | |
| SCHEMBL2014567 | 0.76 | FAAH (0.48) | TSHRHPGDEPHX2FAAHBCHE | |
| SCHEMBL2010166 | 0.74 | MEN1 (0.43) | TSHRHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |