Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795481 | 0.90 | MAOB (0.49) | NR4A2MAOBMRGPRX4FFAR4ALDH1A1 | |
| SCHEMBL9795318 | 0.88 | MAPT (0.54) | NR4A2MAOBFFAR4ALDH1A1L3MBTL1 | |
| SCHEMBL9795357 | 0.87 | MRGPRX4 (0.50) | NR4A2MRGPRX4ALDH1A1L3MBTL1GAA | |
| SCHEMBL3455157 | 0.82 | KDM4E (0.52) | NR4A2MAOBMRGPRX4FFAR4FFAR1 | |
| SCHEMBL9852638 | 0.81 | MAOB (0.47) | NR4A2MAOBMRGPRX4FFAR4ALDH1A1 | |
| SCHEMBL9876508 | 0.80 | NR4A2 (0.45) | NR4A2MAOBMRGPRX4FFAR4ALDH1A1 | |
| SCHEMBL15119869 | 0.75 | NR4A2 (0.51) | NR4A2MAOBMRGPRX4FFAR4FFAR1 | |
| SCHEMBL7823506 | 0.74 | L3MBTL1 (0.77) | NR4A2MAOBMRGPRX4FFAR4ALDH1A1 | |
| SCHEMBL1398676 | 0.73 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23135737 | 0.73 | CYP1A2 (0.58) | NR4A2MAOBMRGPRX4FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057142-A | Herbicidal thiazolecarboxamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| EP-0422470-A2 | Thiazolcarboxylic acid amide derivatives | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |