SCHEMBL9795646

SCHEMBL9795646

c1ccc(C2Nc3ccccc3N2c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.51
RAB9A P51151 3/20 0.51
ABCB1 P08183 2/20 0.41
ALDH1A1 P00352 11/20 0.40
HPGD P15428 9/20 0.40
TDP1 Q9NUW8 3/20 0.40
ALOX12 P18054 2/20 0.40
PKM P14618 1/20 0.40
BRD4 O60885 1/20 0.40
MAPT P10636 4/20 0.39
HSD17B10 Q99714 5/20 0.39
ALOX15 P16050 2/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GAA P10253 3/20 0.39
GLA P06280 2/20 0.39
HTT P42858 1/20 0.39
RGS12 O14924 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360687 1.00 KDM4E (0.51) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL22444376 0.98 KDM4E (0.50) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL10023111 0.91 RAB9A (0.47) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL19675068 0.90 RAB9A (0.50) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL19383742 0.89 KDM4E (0.49) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL457928 0.89 RAB9A (0.49) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL19628225 0.89 RAB9A (0.49) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL18597389 0.85 ABCB1 (0.50) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL12197849 0.85 RAB9A (0.49) KDM4ERAB9AABCB1ALDH1A1HPGD
SCHEMBL20248574 0.85 MEN1 (0.42) KDM4ERAB9AALDH1A1HPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3459956-A2 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-03-27 EP disclosed
US-5017686-A Production of aromatic polyamide using a fused ring stabilizer HUELS AKTIENGESELLSCHAFT (DE) 1991-05-21 US disclosed