SCHEMBL457928

SCHEMBL457928

Brc1ccc(C2Nc3ccccc3N2c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 9/20 0.43
ABCB1 P08183 4/20 0.40
ALDH1A1 P00352 7/20 0.39
MAPT P10636 4/20 0.38
HPGD P15428 4/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
TDP1 Q9NUW8 2/20 0.36
GAA P10253 1/20 0.36
HSD17B10 Q99714 3/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HTT P42858 2/20 0.35
ALOX15 P16050 1/20 0.35
POLB P06746 1/20 0.35
XBP1 P17861 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9795646 0.89 KDM4E (0.51) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL29360687 0.89 KDM4E (0.51) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL15856900 0.88 KDM4E (0.47) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL22444376 0.87 KDM4E (0.50) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL19675068 0.86 RAB9A (0.50) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL19628225 0.84 RAB9A (0.49) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL20248574 0.84 MEN1 (0.42) RAB9AKDM4EALDH1A1MAPTHPGD
SCHEMBL10023111 0.83 RAB9A (0.47) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL12197849 0.81 RAB9A (0.49) RAB9AKDM4EABCB1ALDH1A1MAPT
SCHEMBL13350159 0.81 RAB9A (0.46) RAB9AKDM4EABCB1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833282-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-10 US disclosed
WO-2019004787-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
WO-2019004782-A1 ORGANIC LIGHT EMITTING ELEMENT 주식회사 엘지화학 2019-01-03 WO disclosed
EP-2448925-B1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORP (JP) 2017-12-06 EP disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
EP-3214085-A2 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME Heesung Material Ltd. (KR) 2017-09-06 EP disclosed
WO-2017146466-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-08-31 WO disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
EP-2723721-B1 POLYPHENYLENE HOST COMPOUNDS NITTO DENKO CORP (JP) 2017-08-09 EP disclosed
US-20150287934-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
WO-2014093353-A1 ORGANIC LIGHT EMITTING POLYAROMATIC AND POLYHETEROAROMATIC HOST MATERIALS NITTO DENKO CORPORATION (JP) 2014-06-19 WO disclosed
US-8697885-B2 Carbazole compound, light-emitting element material, organic semiconductor material, light-emitting element, light emitting device, lighting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-15 US disclosed
US-8673459-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
WO-2013155483-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTTED QUINQUIESPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2013-10-17 WO disclosed
WO-2013122364-A2 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE THEREWITH 덕산하이메탈(주) (KR) 2013-08-22 WO disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed
EP-2392563-A1 Nitrogen containing polycyclic derivatives useful in organic light-emitting devices Samsung Mobile Display Co., Ltd. (KR) 2011-12-07 EP disclosed
US-20090184633-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833282-B2 Light-emitting element and electronic device SLC39A3, SLC19A2, SLC39A14 RAB9A 3195/4885KDM4E 2737/4885ABCB1 761/4885
US-20090184633-A1 Quinoxaline Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Quinoxaline Derivative H1-0, NQO2, GDI1 RAB9A 711/4885KDM4E 443/4885ABCB1 2750/4885
US-20150287934-A1 Light-Emitting Element and Electronic Device SLC39A3, SLC19A2, SLC39A14 RAB9A 3195/4885KDM4E 2737/4885ABCB1 761/4885
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL RAB9A 4046/4885KDM4E 2930/4885ABCB1 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.