Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mepanipyrim SCHEMBL29672635 | 0.81 | TAAR1 (0.55) | TAAR1SLC2A1ALDH1A1CDK2KCNH3 | |
| Mepanipyrim SCHEMBL22040 | 0.81 | TAAR1 (0.55) | TAAR1SLC2A1ALDH1A1CDK2KCNH3 | |
| SCHEMBL9795701 | 0.79 | MAPT (0.49) | TAAR1ALDH1A1CDK2KCNH3MEN1 | |
| Mepanipyrim SCHEMBL28756483 | 0.79 | TAAR1 (0.54) | TAAR1SLC2A1ALDH1A1CDK2KCNH3 | |
| SCHEMBL3244058 | 0.79 | TAAR1 (0.69) | TAAR1SLC2A1ALDH1A1TGM2CDK2 | |
| SCHEMBL6791894 | 0.79 | TAAR1 (0.73) | TAAR1SLC2A1ALDH1A1TGM2CDK2 | |
| SCHEMBL9796156 | 0.77 | CDK2 (0.43) | TAAR1ALDH1A1CDK2KCNH3MEN1 | |
| Mepanipyrim SCHEMBL26109940 | 0.75 | TAAR1 (0.49) | TAAR1SLC2A1ALDH1A1CDK2KCNH3 | |
| Mepanipyrim SCHEMBL28515840 | 0.75 | RAB9A (0.50) | TAAR1SLC2A1ALDH1A1TGM2CDK2 | |
| Mepanipyrim SCHEMBL9795913 | 0.74 | TAAR1 (0.48) | TAAR1SLC2A1ALDH1A1TGM2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988704-A | Pyrimidine fungicides for plants | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0224339-B1 | PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING SAME AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTAINING SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |
| US-4814338-A | ANILINO PYRIMIDINE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| EP-0224339-A2 | Pyrimidine derivative, process for preparing same and agricultural or horticultural fungicidal composition containing same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |