Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796301 | 0.89 | CNR2 (0.36) | CNR2CYSLTR2CYSLTR1 | |
| SCHEMBL9796286 | 0.88 | CYSLTR2 (0.37) | CNR2PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL9795950 | 0.85 | PRKCA (0.36) | CNR2PPARGPPARA | |
| SCHEMBL9796092 | 0.83 | AOC3 (0.39) | PPARGPPARA | |
| SCHEMBL28627988 | 0.77 | POLB (0.47) | CNR2PPARGPPARA | |
| SCHEMBL10638974 | 0.77 | MAPK1 (0.43) | CYSLTR2CYSLTR1 | |
| SCHEMBL9796116 | 0.76 | KDM4E (0.44) | — | |
| SCHEMBL15155229 | 0.76 | PRKCA (0.40) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL15155209 | 0.76 | PRKCA (0.40) | PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL16672537 | 0.76 | EPHX1 (0.40) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006534-A | Substituted ethers, thioethers and amines for use as lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0224086-B1 | SUBSTITUTED BENZYL ETHERS | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| EP-0224086-A2 | Substituted benzyl ethers | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |