Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796301 | 0.99 | CNR2 (0.36) | CYSLTR2CYSLTR1ALDH1A1LTB4RCNR2 | |
| SCHEMBL9795950 | 0.95 | PRKCA (0.36) | PPARGPPARAPTGESALOX5CNR2 | |
| SCHEMBL15155229 | 0.89 | PRKCA (0.40) | CYSLTR2CYSLTR1PPARGALDH1A1PPARA | |
| SCHEMBL15155209 | 0.89 | PRKCA (0.40) | CYSLTR2CYSLTR1PPARGALDH1A1PPARA | |
| SCHEMBL15155815 | 0.89 | PRKCA (0.40) | CYSLTR2CYSLTR1PPARGALDH1A1PPARA | |
| SCHEMBL9796233 | 0.88 | CNR2 (0.36) | CYSLTR2CYSLTR1PPARGPPARACNR2 | |
| SCHEMBL9796345 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LTB4R | |
| SCHEMBL5046764 | 0.83 | LTA4H (0.38) | CYSLTR2CYSLTR1ALDH1A1CNR2 | |
| SCHEMBL9796152 | 0.82 | AOC3 (0.40) | PPARGALDH1A1PPARAALOX5 | |
| SCHEMBL9340624 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006534-A | Substituted ethers, thioethers and amines for use as lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |