Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796408 | 0.87 | TDP1 (0.35) | TDP1CTSBKMT2AMAPK1CYP4F2 | |
| SCHEMBL9796389 | 0.86 | TDP1 (0.42) | TDP1CTSBKMT2AMAPTCYP1A2 | |
| SCHEMBL9495720 | 0.86 | TDP1 (0.42) | TDP1CTSBKMT2AMAPTCYP1A2 | |
| SCHEMBL9706684 | 0.84 | MAPK1 (0.48) | TDP1CTSBKMT2AMAPTCYP1A2 | |
| SCHEMBL9706679 | 0.76 | TDP1 (0.65) | TDP1CTSBKMT2AMAPTCYP1A2 | |
| SCHEMBL9796374 | 0.72 | BAZ2B (0.34) | MAPTCYP1A2BAZ2BBAZ2AHPGD | |
| SCHEMBL9495601 | 0.72 | TDP1 (0.39) | TDP1CTSBKMT2AMAPTMAPK1 | |
| SCHEMBL6908332 | 0.72 | ALDH1A1 (0.39) | TDP1CTSBKMT2AMAPK1CYP4F2 | |
| SCHEMBL6699195 | 0.71 | CYP4F2 (0.44) | TDP1CTSBKMT2AMAPTCYP1A2 | |
| SCHEMBL9495511 | 0.71 | GUSB (0.33) | MAPTCYP1A2BAZ2BBAZ2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041156-A | 3-aryluracils for the control of weeds | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |