Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796511 | 0.97 | SLC6A2 (0.54) | UTS2RSLC6A2SLC6A4DRD3DRD2 | |
| Oxalic Acid SCHEMBL10675334 | 0.90 | UTS2R (0.56) | UTS2RSLC6A2SLC6A4DRD3DRD2 | |
| Oxalic Acid SCHEMBL10672534 | 0.90 | UTS2R (0.57) | UTS2RSLC6A2SLC6A4DRD3DRD2 | |
| SCHEMBL9796588 | 0.89 | UTS2R (0.57) | UTS2RSLC6A2SLC6A4DRD3ROCK2 | |
| SCHEMBL9796574 | 0.89 | UTS2R (0.57) | UTS2RSLC6A2SLC6A4DRD3ROCK2 | |
| SCHEMBL9796534 | 0.88 | ROCK2 (0.58) | UTS2RSLC6A2SLC6A4DRD3ROCK2 | |
| SCHEMBL9796206 | 0.87 | UTS2R (0.53) | UTS2RSLC6A4DRD3ROCK2ROCK1 | |
| Oxalic Acid SCHEMBL9796554 | 0.87 | UTS2R (0.48) | UTS2RSLC6A2SLC6A4ROCK2ROCK1 | |
| Fumaric Acid SCHEMBL10679564 | 0.84 | UTS2R (0.53) | UTS2RSLC6A2SLC6A4DRD3ROCK2 | |
| Fumaric Acid SCHEMBL10679559 | 0.84 | UTS2R (0.53) | UTS2RSLC6A2SLC6A4DRD3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256181-B1 | NOVEL QUINALDINAMIDE DERIVATIVES AND THEIR PREPARATIONS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4764617-A | MUSCLE RELAXANTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0256181-A1 | Novel quinaldinamide derivatives and their preparations | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-02-24 | — | — | EP | disclosed |