Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10675334 | 0.97 | UTS2R (0.56) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL9796574 | 0.92 | UTS2R (0.57) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL9796588 | 0.92 | UTS2R (0.57) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL9796534 | 0.91 | ROCK2 (0.58) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL9796511 | 0.89 | SLC6A2 (0.54) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL9796406 | 0.89 | HTR1A (0.51) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL10672534 | 0.89 | UTS2R (0.57) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| Fumaric Acid SCHEMBL10679559 | 0.87 | UTS2R (0.53) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| Fumaric Acid SCHEMBL10679564 | 0.87 | UTS2R (0.53) | UTS2RSLC6A4ROCK2ROCK1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL9796544 | 0.87 | UTS2R (0.54) | UTS2RSLC6A4ROCK2ROCK1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256181-B1 | NOVEL QUINALDINAMIDE DERIVATIVES AND THEIR PREPARATIONS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-01-23 | — | — | EP | claimed |
| US-4764617-A | MUSCLE RELAXANTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-08-16 | — | — | US | claimed |
| EP-0256181-A1 | Novel quinaldinamide derivatives and their preparations | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-02-24 | — | — | EP | claimed |
| EP-0256181-B1 | NOVEL QUINALDINAMIDE DERIVATIVES AND THEIR PREPARATIONS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4764617-A | MUSCLE RELAXANTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0256181-A1 | Novel quinaldinamide derivatives and their preparations | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-02-24 | — | — | EP | disclosed |