Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ATM | Q13315 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MDM4 | O15151 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | MAOA | P21397 | 4/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979659 | 1.00 | LMNA (0.61) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL1225595 | 0.86 | LMNA (0.65) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL1225597 | 0.86 | LMNA (0.65) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL31463107 | 0.85 | KMT2A (0.80) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL979466 | 0.84 | LMNA (0.62) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL979467 | 0.84 | LMNA (0.62) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL6340416 | 0.84 | MAOA (0.55) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL6340414 | 0.84 | MAOA (0.55) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL1224283 | 0.83 | MAOB (0.72) | LMNAHPGDATMSMN1; SMN2ALOX12 | |
| SCHEMBL1224286 | 0.83 | MAOB (0.72) | LMNAHPGDATMSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114521553-B | Special antifeedant for preventing and controlling insect gall thrips on ficus plants | 福建省农业科学院植物保护研究所 | 2023-04-25 | — | — | CN | claimed |
| CN-114521553-A | A special food refusal for preventing and controlling insect thrips on Ficus plant | 福建省农业科学院植物保护研究所 | 2022-05-24 | — | — | CN | claimed |
| CN-114521553-B | Special antifeedant for preventing and controlling insect gall thrips on ficus plants | 福建省农业科学院植物保护研究所 | 2023-04-25 | — | — | CN | disclosed |
| CN-114521553-B | Special antifeedant for preventing and controlling insect gall thrips on ficus plants | 福建省农业科学院植物保护研究所 | 2023-04-25 | — | — | CN | disclosed |
| CN-114521553-A | A special food refusal for preventing and controlling insect thrips on Ficus plant | 福建省农业科学院植物保护研究所 | 2022-05-24 | — | — | CN | disclosed |
| CN-114521553-A | A special food refusal for preventing and controlling insect thrips on Ficus plant | 福建省农业科学院植物保护研究所 | 2022-05-24 | — | — | CN | disclosed |
| US-7872029-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP | 2011-01-18 | — | — | US | disclosed |
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Robinson, Thomas Philip (US) | 2009-01-15 | — | — | US | disclosed |
| US-7432303-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Bowen, J. Phillip (US) | 2008-10-07 | — | — | US | disclosed |
| US-20050148599-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2005-07-07 | — | — | US | disclosed |
| US-6906105-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP (US) | 2005-06-14 | — | — | US | disclosed |
| US-6462075-B1 | USE OF CHALCONE AND ITS DERIVATIVES AS ANTITUMOR/ANTICANCER AGENTS AND TO TREAT A NUMBER OF CONDITIONS OR DISEASE STATES IN WHICH ANGIOGENESIS IS A FACTOR INCLUDING PSORIASIS, ACNE, ROSACEA, WARTS, ECZEMA, HEMANGIOMAS AND LYMPHANGIOGENESIS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2002-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, FLT4, VEGFA | LMNA 3495/4885HPGD 320/4885ATM 3910/4885 |
| US-20050148599-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, VEGFA, FLT4 | LMNA 2184/4885HPGD 57/4885ATM 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.