SCHEMBL9796995

SCHEMBL9796995

C=CCC(CCl)(C(=O)OCC)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.56
HTT P42858 1/20 0.54
PIN1 Q13526 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.38
MMP8 P22894 1/20 0.38
POLB P06746 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 2/20 0.36
THRB P10828 1/20 0.36
ATM Q13315 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10951249 0.80 ALDH1A1 (0.50) ALDH1A1TSHRHTTPIN1KMT2A
SCHEMBL3617440 0.78 HTT (0.50) ALDH1A1TSHRHTTPIN1KMT2A
SCHEMBL3617442 0.78 HTT (0.50) ALDH1A1TSHRHTTPIN1KMT2A
SCHEMBL7490885 0.77 ALDH1A1 (0.51) ALDH1A1TSHRHTTPIN1KMT2A
SCHEMBL2656929 0.77 ALDH1A1 (0.46) ALDH1A1TSHRHTTPIN1KMT2A
SCHEMBL8483586 0.77 PIN1 (0.53) ALDH1A1TSHRPIN1KMT2AMEN1
SCHEMBL11849356 0.77 HPGD (0.46) ALDH1A1TSHRHTTPIN1KMT2A
SCHEMBL3999764 0.76 ALDH1A1 (0.67) ALDH1A1TSHRHTTKMT2AMEN1
Ammonia Solution, Strong SCHEMBL10879989 0.76 PIN1 (0.51) ALDH1A1TSHRPIN1KMT2AMEN1
SCHEMBL10747932 0.75 ALDH1A1 (0.61) ALDH1A1TSHRHTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4999451-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-03-12 US disclosed
US-4833266-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-05-23 US disclosed
US-4681953-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-07-21 US disclosed
US-4454343-A Intermediates in a process for preparing dihalovinylcyclopropanecarboxylates FMC CORPORATION (US) 1984-06-12 US disclosed
US-4214097-A Process for preparing dihalovinylcyclopropanecarboxylates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1980-07-22 US disclosed