Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797004 | 1.00 | LMNA (0.65) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL29246835 | 0.84 | LMNA (0.67) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL2168536 | 0.84 | LMNA (0.67) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL2170337 | 0.84 | LMNA (0.67) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL2168541 | 0.84 | LMNA (0.67) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL3683589 | 0.82 | LMNA (0.65) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL3683588 | 0.82 | LMNA (0.65) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL10828657 | 0.82 | LMNA (0.75) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL11444513 | 0.82 | LMNA (0.75) | LMNATSHRTDP1MEN1KMT2A | |
| SCHEMBL10778297 | 0.82 | LMNA (0.75) | LMNATSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999451-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-03-12 | — | — | US | disclosed |
| US-4833266-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-05-23 | — | — | US | disclosed |
| US-4681953-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-07-21 | — | — | US | disclosed |
| US-4454343-A | Intermediates in a process for preparing dihalovinylcyclopropanecarboxylates | FMC CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4214097-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-07-22 | — | — | US | disclosed |