Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456627 | 0.84 | CXCR4 (0.52) | KMT2ASMN1; SMN2MEN1SIRT2SIRT1 | |
| SCHEMBL24718266 | 0.80 | SIRT2 (0.48) | KMT2ASIRT2SIRT1P2RX7TRPC5 | |
| Nebracetam SCHEMBL195354 | 0.79 | HPGD (0.60) | KMT2ASMN1; SMN2MAPTP2RX7HPGD | |
| SCHEMBL9456736 | 0.77 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2MEN1HPGDTSHR | |
| SCHEMBL13950136 | 0.72 | ACHE (0.59) | KMT2ASMN1; SMN2MEN1MAPTP2RX7 | |
| SCHEMBL9456892 | 0.72 | HPGD (0.44) | KMT2ASMN1; SMN2P2RX7HPGDTSHR | |
| SCHEMBL10639529 | 0.71 | ALDH1A1 (0.49) | KMT2ASMN1; SMN2MEN1SIRT2SIRT1 | |
| SCHEMBL9456386 | 0.71 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2MEN1SIRT2SIRT1 | |
| Nebracetam SCHEMBL1030649 | 0.71 | HPGD (0.51) | KMT2ASMN1; SMN2MAPTP2RX7HPGD | |
| Nebracetam SCHEMBL1030651 | 0.71 | HPGD (0.51) | KMT2ASMN1; SMN2MAPTP2RX7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073671-A | Nootropic and antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1991-12-17 | — | — | US | disclosed |