Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.49 |
| ▸ | DRD5 | P21918 | 7/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | DRD3 | P35462 | 6/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9797187 | 0.99 | DRD1 (0.48) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL9797639 | 0.90 | SIGMAR1 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL9797385 | 0.89 | SIGMAR1 (0.43) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL9797661 | 0.89 | SIGMAR1 (0.47) | DRD1DRD5DRD2DRD3DRD4 | |
| Bromide SCHEMBL9797412 | 0.88 | SIGMAR1 (0.42) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL9797504 | 0.88 | SLC6A2 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL9797496 | 0.84 | SLC6A2 (0.45) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL9797168 | 0.83 | SLC6A2 (0.44) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL9797273 | 0.82 | CYP3A4 (0.57) | SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL3697299 | 0.82 | SIGMAR1 (0.49) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988690-A | Antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-01-29 | — | — | US | claimed |