Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715151 | 0.93 | PTGS2 (0.43) | ALDH1A1HSD17B10LPLLIPGGPR3 | |
| SCHEMBL9797935 | 0.88 | CNR1 (0.39) | CA2LPLLIPG | |
| SCHEMBL1741603 | 0.80 | SKP2 (0.48) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL15066937 | 0.80 | SKP2 (0.44) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL972794 | 0.79 | — | — | |
| SCHEMBL677715 | 0.78 | SKP2 (0.43) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL11134188 | 0.77 | NPC1 (0.50) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL11030323 | 0.77 | SKP2 (0.42) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL6885851 | 0.77 | SKP2 (0.46) | SKP2HPGDNPC1MAPK1HTT | |
| SCHEMBL4432930 | 0.77 | SKP2 (0.42) | SKP2HPGDNPC1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275501-B1 | PROCESS FOR THE PREPARATION OF (Z)-2-(2-ARYLETHENYL)-ARYLCARBOXYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4857658-A | Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0155482-A1 | Azo dyestuffs comprising pyridinoisothiazole radicals | BASF Aktiengesellschaft (DE) | 1985-09-25 | — | — | EP | disclosed |
| US-4277472-A | 3,6-Disubstituted-5,7-(lower alkano)-5,6,7,8-tetrahydropyrido(4,3-C)pyridazines; their intermediates, preparation, antihypertensive use and compositions | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-07-07 | — | — | US | disclosed |
| EP-0015512-A1 | Thiazole dispersion dyestuffs | BASF Aktiengesellschaft (DE) | 1980-09-17 | — | — | EP | disclosed |
| US-4207233-A | Azo dyes containing a thiazole component | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |
| US-4108982-A | DIURETICS, HYPOTENSIVE AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1978-08-22 | — | — | US | disclosed |
| US-4093812-A | MICROBIOCIDES, DISINFECTANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1978-06-06 | — | — | US | disclosed |