SCHEMBL677715

SCHEMBL677715

CCCCc1[c]ccc(CCCC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.43
HPGD P15428 2/20 0.42
NPC1 O15118 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LPL P06858 2/20 0.36
LIPG Q9Y5X9 2/20 0.36
PSMB5 P28074 1/20 0.36
PTGS2 P35354 3/20 0.35
CYP3A4 P08684 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1777578 0.94 PTGS2 (0.43) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL677464 0.94 PTGS2 (0.42) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL1775603 0.94 SKP2 (0.38) SKP2HPGDNPC1MAPK1HTT
SCHEMBL2089194 0.92 PTGS2 (0.44) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL1778966 0.92 PTGS2 (0.44) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL22264051 0.92 PTGS2 (0.41) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL283991 0.92 PTGS2 (0.44) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL827972 0.92 PTGS2 (0.44) ALDH1A1HSD17B10LPLLIPGPTGS2
SCHEMBL11030323 0.90 SKP2 (0.42) SKP2HPGDNPC1MAPK1HTT
SCHEMBL1779587 0.90 SKP2 (0.34) SKP2HPGDNPC1MAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307593-A Tri-dentate phosphinopyrrolimine ligand, preparation method thereof, ethylene oligomerization catalyst and application thereof 万华化学集团股份有限公司 2024-07-09 CN claimed
CN-114933613-B Preparation of PNNP ligand, ethylene oligomerization catalyst and application thereof 万华化学集团股份有限公司 2024-02-27 CN claimed
CN-117466940-A Cyperus rotundus L ligand and application thereof in preparation of chiral beta-butyrolactone 万华化学集团股份有限公司 2024-01-30 CN claimed
CN-116970107-A Catalyst combination and method for preparing poly alpha-olefin synthetic oil by using same 万华化学集团股份有限公司 2023-10-31 CN claimed
CN-116903772-A Method for preparing polyolefin plastomer 万华化学集团股份有限公司 2023-10-20 CN claimed
CN-114315905-B Preparation of PCPN ligand, ethylene oligomerization catalyst and application thereof 万华化学集团股份有限公司 2023-10-20 CN claimed
CN-116899622-A High-selectivity catalyst for ethylene oligomerization and application thereof 万华化学集团股份有限公司 2023-10-20 CN claimed
CN-114920866-B Preparation method of polyolefin thermoplastic elastomer 万华化学集团股份有限公司 2023-07-14 CN claimed
CN-116284125-A Norbornene PCNP ligand, preparation method and application thereof 万华化学集团股份有限公司 2023-06-23 CN claimed
CN-113354683-B Biphosphine ligand, preparation method and application thereof 万华化学集团股份有限公司 2023-05-30 CN claimed
US-20080223444-A1 Perylene Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof GEORGIA TECH RESEARCH CORPORATION 2008-09-18 US claimed
WO-2006093965-A2 CORONENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2006-09-08 WO claimed
CN-1247492-C Cobalt catalyst composition for ethylene oligomerization and application thereof CHINA NAT PETROLEUM CORP (CN) 2006-03-29 CN claimed
WO-2005124453-A2 PERYLENE CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2005-12-29 WO claimed
CN-1202049-C Iron-based catalyst composition for ethylene oligomerization and application thereof CHINA NAT PETROLEUM CORP (CN) 2005-05-18 CN claimed
CN-1463800-A Binuclear cobalt catalyst composition for synthesizing linear alpha-olefin by ethylene oligomerization and method for preparing linear alpha-olefin PETROCHINA CO LTD (CN) 2003-12-31 CN claimed
CN-1463799-A Binuclear iron-based catalyst composition for preparing alpha-olefin by ethylene oligomerization and method for preparing linear alpha-olefin PETROCHINA CO LTD (CN) 2003-12-31 CN claimed
CN-1403424-A Cobalt catalyst composition for ethylene oligomerization and preparation method of alpha-olefin CHINA NAT PETROLEUM CORP (CN) 2003-03-19 CN claimed
CN-1374281-A Iron-based catalyst composition for ethylene oligomerization and preparation method of alpha-olefin CHINA PETROLEUM CORP (CN) 2002-10-16 CN claimed
CN-1324419-A Inhibition of pulp and paper yellowing using hydroxylamines and other coadditives CIBA SC HOLDING AG (CH) 2001-11-28 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080223444-A1 Perylene Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof SLC43A1, SLC3A2, SLC16A3 SKP2 4774/4885HPGD 2088/4885NPC1 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.