Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 7/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433892 | 0.89 | CTSL (0.62) | HDAC1HDAC2CTSLTGM2ITGA4 | |
| SCHEMBL8433969 | 0.89 | CTSL (0.62) | HDAC1HDAC2CTSLTGM2ITGA4 | |
| SCHEMBL8436808 | 0.89 | CTSL (0.62) | HDAC1HDAC2CTSLTGM2ITGA4 | |
| SCHEMBL11556459 | 0.88 | HDAC1 (0.57) | HDAC1HDAC2CTSLTGM2ITGA4 | |
| SCHEMBL17446787 | 0.87 | IDO1 (0.57) | CTSLCTSB | |
| SCHEMBL8432473 | 0.86 | CTSL (0.65) | HDAC1HDAC2CTSLCTSB | |
| SCHEMBL8432468 | 0.86 | CTSL (0.65) | HDAC1HDAC2CTSLCTSB | |
| SCHEMBL14050011 | 0.86 | HDAC1 (0.55) | HDAC1HDAC2CTSLTGM2ITGA4 | |
| SCHEMBL951558 | 0.84 | CTSL (0.65) | CTSLTGM2ITGA4ITGB7P2RX7 | |
| SCHEMBL11138908 | 0.84 | CTSL (0.65) | CTSLTGM2ITGA4ITGB7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030732-A | Antiacterial agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |