SCHEMBL5154816

SCHEMBL5154816

O=C(Nc1ccc(Cc2ccc(NC(=O)c3ccccc3)cc2)cc1)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.69
NPC1 O15118 5/20 0.67
RAB9A P51151 5/20 0.67
MEN1 O00255 3/20 0.67
KMT2A Q03164 3/20 0.67
KDM4E B2RXH2 2/20 0.67
POLB P06746 2/20 0.67
SIRT1 Q96EB6 1/20 0.67
SMN1; SMN2 Q16637 2/20 0.65
MAPT P10636 1/20 0.65
CACNA1B Q00975 1/20 0.62
APBA1 Q02410 1/20 0.62
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
NR1H4 Q96RI1 1/20 0.61
PRMT1 Q99873 1/20 0.61
FFAR1 O14842 1/20 0.61
PGR P06401 1/20 0.61
LMNA P02545 1/20 0.60
MAPK1 P28482 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31432639 0.92 MEN1 (0.77) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL126415 0.88 PTPN1 (0.87) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL5400199 0.87 PTPN1 (0.67) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL840495 0.87 PTPN1 (0.67) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL12605376 0.86 NPC1 (0.62) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL18103163 0.86 NPC1 (0.88) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL14715824 0.86 NPC1 (0.88) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL13185636 0.85 NPC1 (0.68) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL8143801 0.85 NR1H4 (0.82) PTPN1NPC1RAB9AMEN1KMT2A
SCHEMBL1857575 0.85 PTPN1 (0.65) PTPN1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630693-B2 Small-cell polystyrene foams, and process for producing same INEOS STYROLUTION GROUP GMBH (DE) 2026-05-19 US disclosed
EP-4153668-B1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS STYROLUTION GROUP GMBH (DE) 2024-08-28 EP disclosed
US-20240244882-A1 DISPLAY DEVICE AND MANUFACTURING METHOD OF DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-07-18 US disclosed
US-20230403920-A1 METHOD OF MANUFACTURING DISPLAY PANEL AND THE DISPLAY PANEL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-12-14 US disclosed
US-20230276700-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-08-31 US disclosed
US-20230227627-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS STYROLUTION GROUP GMBH (DE) 2023-07-20 US disclosed
US-10450265-B2 Method for producing amides or polyamides by using aromatic carbamates by way of isocyanates as precursors through catalyzed thermal processes and method for producing aromatic carbamate precursors from aromatic amines GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) 2019-10-22 US disclosed
US-20180186918-A1 MULTI-FUNCTIONAL CARBAMATE HAVING SOFT-SEGMENTS, POLYISOCYANATE OBTAINED VIA SUBSEQUENT NON-PHOSGENE SYNTHESIS METHODS, URETHANE PREPOLYMER AND ELASTOMERIC URETHANE HAVING SOFT-SEGMENTS DERIVED THEREFROM, AND PREPARATION METHOD THEREOF GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) 2018-07-05 US disclosed
US-20180186918-A1 MULTI-FUNCTIONAL CARBAMATE HAVING SOFT-SEGMENTS, POLYISOCYANATE OBTAINED VIA SUBSEQUENT NON-PHOSGENE SYNTHESIS METHODS, URETHANE PREPOLYMER AND ELASTOMERIC URETHANE HAVING SOFT-SEGMENTS DERIVED THEREFROM, AND PREPARATION METHOD THEREOF GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) 2018-07-05 US disclosed
US-20180163061-A1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-14 US disclosed
US-20160280851-A1 IMINOETHER COMPOUND, POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCING CARBOXYLIC ACID ESTER, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE, AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
EP-2204408-B1 POLYOLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2015-02-25 EP disclosed
US-8420721-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2013-04-16 US disclosed
US-20100240815-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-09-23 US disclosed
EP-2204408-A1 POLYOLEFIN RESIN COMPOSITION Adeka Corporation (JP) 2010-07-07 EP disclosed
EP-1226209-B1 A COMBINATION OF A SOLID SOLVENT AND A MELT-PROCESSIBLE BLOCK COPOLYMER GORE ENTERPRISE HOLDINGS INC (US) 2007-01-10 EP disclosed
EP-1226209-A1 A COMBINATION OF A SOLID SOLVENT AND A MELT-PROCESSIBLE BLOCK COPOLYMER Gore Enterprise Holdings, Inc. (US) 2002-07-31 EP disclosed
US-6387994-B1 MIXTURES W. L. GORE & ASSOCIATES, INC. 2002-05-14 US disclosed
WO-2001032763-A1 A COMBINATION OF A SOLID SOLVENT AND A MELT-PROCESSIBLE BLOCK COPOLYMER GORE ENTERPRISE HOLDINGS, INC. (US) 2001-05-10 WO disclosed
EP-0776933-B1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEM CO LTD (JP) 1999-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10450265-B2 Method for producing amides or polyamides by using aromatic carbamates by way of isocyanates as precursors through catalyzed thermal processes and method for producing aromatic carbamate precursors from aromatic amines NAAA, NISCH, CPS1 PTPN1 3790/4885NPC1 2925/4885RAB9A 3109/4885
US-20180186918-A1 MULTI-FUNCTIONAL CARBAMATE HAVING SOFT-SEGMENTS, POLYISOCYANATE OBTAINED VIA SUBSEQUENT NON-PHOSGENE SYNTHESIS METHODS, URETHANE PREPOLYMER AND ELASTOMERIC URETHANE HAVING SOFT-SEGMENTS DERIVED THEREFROM, AND PREPARATION METHOD THEREOF PUF60, NOTUM, PFAS PTPN1 1442/4885NPC1 4639/4885RAB9A 4786/4885
US-20160280851-A1 IMINOETHER COMPOUND, POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCING CARBOXYLIC ACID ESTER, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE, AND SOLAR CELL MODULE BRS3, RAD1, RAD51 PTPN1 4657/4885NPC1 4411/4885RAB9A 1748/4885
US-20230227627-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME F12, FDFT1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 PTPN1 3864/4885NPC1 1606/4885RAB9A 3345/4885
US-12630693-B2 Small-cell polystyrene foams, and process for producing same H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CBR3 PTPN1 3426/4885NPC1 1529/4885RAB9A 3103/4885
US-20230276700-A1 Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SLC43A1, SLC7A5, SLCO4C1 PTPN1 4762/4885NPC1 1094/4885RAB9A 1214/4885
US-20180163061-A1 CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLC26A3 PTPN1 4270/4885NPC1 297/4885RAB9A 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.