Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798363 | 1.00 | KDM1A (0.41) | KDM1AGRM2CYP11B1CYP11B2DGAT1 | |
| SCHEMBL9798237 | 0.87 | CYP11B2 (0.40) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL9798231 | 0.87 | CYP11B2 (0.40) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL9798130 | 0.86 | DGAT1 (0.41) | KDM1ACYP11B1CYP11B2DGAT1NPC1 | |
| SCHEMBL8382934 | 0.86 | KDM1A (0.43) | KDM1AGRM2CYP11B1CYP11B2NPC1 | |
| SCHEMBL9798138 | 0.86 | DGAT1 (0.41) | KDM1ACYP11B1CYP11B2DGAT1NPC1 | |
| SCHEMBL8382931 | 0.86 | KDM1A (0.43) | KDM1AGRM2CYP11B1CYP11B2NPC1 | |
| SCHEMBL9798177 | 0.86 | DGAT1 (0.42) | KDM1ADGAT1MAOB | |
| SCHEMBL9798188 | 0.86 | DGAT1 (0.42) | KDM1ADGAT1MAOB | |
| SCHEMBL8380281 | 0.86 | KDM1A (0.40) | KDM1AGRM2CYP11B1CYP11B2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772416-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-09-20 | — | — | US | claimed |
| EP-0240320-B1 | PHENYLPYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4772416-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-09-20 | — | — | US | disclosed |