Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698208 | 0.83 | PDE4B (0.42) | MAPK14MAPK11PDE4BCNR1POLB | |
| SCHEMBL10389842 | 0.80 | ALDH1A1 (0.41) | MAPK14CYP2C9CYP2C19KDM4EMEN1 | |
| SCHEMBL10701543 | 0.80 | MEN1 (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL10697955 | 0.77 | ALDH1A1 (0.39) | LMNAPOLBKDM4EMEN1KMT2A | |
| SCHEMBL10701708 | 0.76 | KDM4E (0.44) | LMNAEPHB4POLBNOTUMCYP2C9 | |
| SCHEMBL2853643 | 0.71 | PDE4B (0.43) | MAPK14MAPK11PDE4BPOLBNOTUM | |
| SCHEMBL163226 | 0.70 | FABP3 (0.50) | MAPTSLC16A3 | |
| SCHEMBL10388592 | 0.68 | MALT1 (0.52) | LMNAPOLBMEN1KMT2ATP53 | |
| SCHEMBL10388067 | 0.66 | MAPK1 (0.48) | LMNAPOLBKDM4EMEN1KMT2A | |
| SCHEMBL15428664 | 0.65 | EPHB4 (0.44) | EPHB4NOTUMCYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266569-B1 | SOLVENT DYES WITH CARBOXYLIC-ACID FUNCTIONS | BASF Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0266569-A2 | Solvent dyes with carboxylic-acid functions | BASF Aktiengesellschaft (DE) | 1988-05-11 | — | — | EP | disclosed |