Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853643 | 0.87 | PDE4B (0.43) | PDE4BMAPK11MAPK14RIPK1HPGD | |
| SCHEMBL9798804 | 0.83 | MAPK14 (0.35) | PDE4BMAPK11MAPK14TP53SLC16A3 | |
| SCHEMBL163226 | 0.83 | FABP3 (0.50) | SLC16A3SLC16A1RXRANR1H2NR1H3 | |
| SCHEMBL10388627 | 0.81 | RXRA (0.52) | PDE4BMAPK11MAPK14TP53RIPK1 | |
| SCHEMBL1460412 | 0.77 | HPGD (0.44) | PDE4BMAPK11MAPK14TP53RIPK1 | |
| SCHEMBL10698162 | 0.75 | MEN1 (0.44) | PDE4BMAPK11MAPK14TP53NPC1 | |
| SCHEMBL1302690 | 0.75 | ALDH1A1 (0.40) | PDE4BRIPK1HPGDNPC1RAB9A | |
| SCHEMBL4917405 | 0.74 | KDM4E (0.50) | PDE4BMAPK11MAPK14RIPK1NPC1 | |
| SCHEMBL19356961 | 0.74 | PDE4B (0.44) | PDE4BMAPK11MAPK14TP53HPGD | |
| SCHEMBL2320840 | 0.74 | MARS1 (0.51) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266569-A2 | Solvent dyes with carboxylic-acid functions | BASF Aktiengesellschaft (DE) | 1988-05-11 | — | — | EP | disclosed |