Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30942632 | 0.83 | CHEK1 (0.42) | ALDH1A1DPP4LRRK2PI4KAPI4K2B | |
| SCHEMBL9081 | 0.83 | CHEK1 (0.42) | ALDH1A1DPP4LRRK2PI4KAPI4K2B | |
| Adenine SCHEMBL8820860 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LRRK2PI4KAPI4K2BPI4K2A | |
| Hypoxanthine SCHEMBL11439075 | 0.82 | ALDH1A1 (0.67) | ALDH1A1DPP4LRRK2PI4KAPI4K2B | |
| SCHEMBL9798919 | 0.81 | CHEK1 (0.41) | ALDH1A1DPP4LRRK2PI4KAPI4K2B | |
| Hydrochloric Acid SCHEMBL11162213 | 0.81 | CHEK1 (0.41) | ALDH1A1DPP4LRRK2PI4KAPI4K2B | |
| SCHEMBL8716026 | 0.81 | CHEK1 (0.41) | ALDH1A1DPP4LRRK2PI4KAPI4K2B | |
| Acetone SCHEMBL3279080 | 0.77 | CHEK1 (0.36) | DPP4PARP1FGFR1CDC7DBF4 | |
| Trimethylammonium SCHEMBL8826193 | 0.76 | CHEK1 (0.38) | DPP4LRRK2PDPK1AURKAPRKACA | |
| SCHEMBL11167998 | 0.76 | CHEK1 (0.35) | DPP4LRRK2AURKAPRKACARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016005-A1 | 2'-SUBSTITUTED BETA-ARABINOFURANOSYL NUCLEOSIDES AND NUCLEOTIDES, PREPARATION AND USE THEREOF. | RESEARCH CORP (US) | 1980-10-01 | — | — | EP | disclosed |
| EP-0016005-A4 | 2'-SUBSTITUTED BETA-ARABINOFURANOSYL NUCLEOSIDES AND NUCLEOTIDES, PREPARATION AND USE THEREOF. | RESEARCH CORP (US) | 1980-05-21 | — | — | EP | disclosed |
| WO-1979001068-A1 | 2'-SUBSTITUTED ARABINOFURANOSYL NUCLEOSIDES AND NUCLEOTIDES INTERMEDIATES,PREPARATION AND USE THEREOF | RESEARCH CORP (US) | 1979-12-13 | — | — | WO | disclosed |