Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 6/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531999 | 0.87 | PLA2G4A (0.33) | SMPD1CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL9798660 | 0.84 | PLA2G2C (0.46) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL9798672 | 0.84 | PLA2G2C (0.46) | CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL9529530 | 0.82 | PPARA (0.37) | SMPD1CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL9529528 | 0.82 | PPARA (0.37) | SMPD1CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL9798991 | 0.78 | GMNN (0.41) | CYP2C9FABP3 | |
| SCHEMBL9798998 | 0.78 | GMNN (0.41) | CYP2C9FABP3 | |
| SCHEMBL9529484 | 0.77 | SMPD1 (0.34) | SMPD1PLA2G2APPARAP2RY10PLA2G2C | |
| SCHEMBL9527787 | 0.77 | PLA2G4A (0.35) | SMPD1PPARAP2RY10PLA2G2C | |
| SCHEMBL10771361 | 0.76 | PPARA (0.36) | SMPD1CYP1A2CYP2D6CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |