Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PBK | Q96KB5 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245081 | 0.79 | LMNA (0.42) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5516689 | 0.74 | MAPT (0.37) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4912196 | 0.72 | TSHR (0.39) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5382137 | 0.66 | LMNA (0.42) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25879861 | 0.65 | LMNA (0.38) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31305641 | 0.65 | ACHE (0.50) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL393790 | 0.65 | ACHE (0.50) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2912790 | 0.63 | SELL (0.48) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28823581 | 0.63 | ACHE (0.48) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18109802 | 0.63 | ACHE (0.48) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125059-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-02-27 | — | — | EP | disclosed |
| EP-0095330-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1987-11-19 | — | — | EP | disclosed |
| US-4664693-A | POSTEMERGENCE | ICI AUSTRALIA LIMITED (AU) | 1987-05-12 | — | — | US | disclosed |
| US-4511391-A | Cyclohexane-1,3-dione derivatives and their herbicidal compositions and methods | ICI AUSTRALIA LIMITED (AU) | 1985-04-16 | — | — | US | disclosed |
| EP-0125059-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |
| EP-0095330-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-11-30 | — | — | EP | disclosed |