Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 2/20 | 0.43 |
| ▸ | PNP | P00491 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798192 | 0.91 | HPRT1 (0.50) | HPRT1PNP | |
| SCHEMBL9799070 | 0.89 | PNP (0.50) | HPRT1PNPALDH1A1HSD17B10PKM | |
| SCHEMBL9798139 | 0.79 | HPRT1 (0.39) | HPRT1PNP | |
| SCHEMBL10646545 | 0.78 | PNP (0.51) | HPRT1PNPALDH1A1HSD17B10PKM | |
| Hydrochloric Acid SCHEMBL9798343 | 0.77 | PNP (0.50) | HPRT1PNPALDH1A1HSD17B10PKM | |
| SCHEMBL9798158 | 0.75 | PNP (0.50) | HPRT1PNPALDH1A1HSD17B10MAPT | |
| SCHEMBL9799100 | 0.73 | HPRT1 (0.48) | HPRT1PNPSMN1; SMN2 | |
| SCHEMBL2128394 | 0.72 | HPRT1 (0.49) | HPRT1PNP | |
| SCHEMBL9799122 | 0.72 | PNP (0.63) | HPRT1PNPALDH1A1HSD17B10BLM | |
| SCHEMBL10507676 | 0.71 | HPRT1 (0.48) | HPRT1PNPALDH1A1HSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051429-A | For treatment of autoimmune diseases such as arthritis, lupus, antiinflammatory agents, multiple sclerosis, diabetes and viral diseases | WARNER-LAMBERT CO. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0178178-A2 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |