Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799375 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726817 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726825 | 0.72 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726768 | 0.72 | HMGCR (0.36) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726524 | 0.72 | HMGCR (0.36) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726571 | 0.69 | HMGCR (0.35) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726576 | 0.67 | HMGCR (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4683800 | 0.64 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL9726653 | 0.64 | HMGCR (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL9726655 | 0.64 | HMGCR (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |