Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570777 | 0.67 | TSHR (0.40) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL10756100 | 0.67 | ALDH1A1 (0.37) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL12611448 | 0.65 | TSHR (0.52) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL21626316 | 0.63 | TSHR (0.44) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL21508213 | 0.63 | TSHR (0.44) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL1508521 | 0.63 | TSHR (0.44) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL5865831 | 0.63 | TSHR (0.44) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL8985603 | 0.63 | GAA (0.44) | TSHRMAPK1HIF1ATDP1LMNA | |
| Chlorophenothane SCHEMBL27483995 | 0.63 | TSHR (0.75) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL11216942 | 0.62 | TSHR (0.61) | TSHRMAPK1HIF1ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041663-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-5032169-A | Antidotes for herbicides | CIBA-GEIGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| US-4707182-A | Phenoxine-ketal ethers, compositions containing them and the use thereof | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| US-4576628-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |
| US-4566901-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| US-4530716-A | Plant safening agent | CIBA-GEIGY CORPORATION (US) | 1985-07-23 | — | — | US | disclosed |