Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504565 | 0.96 | NPC1 (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL11664466 | 0.96 | NPC1 (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9508417 | 0.96 | NPC1 (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9506640 | 0.96 | NPC1 (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9507747 | 0.96 | NPC1 (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL11413233 | 0.90 | LMNA (0.52) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9799870 | 0.88 | RARB (0.58) | RARBSMN1; SMN2THRATHRBMAPT | |
| SCHEMBL9513365 | 0.85 | THRA (0.57) | SMN1; SMN2THRATHRBMAPTKMT2A | |
| SCHEMBL9762028 | 0.84 | THRA (0.49) | RARBTHRATHRBMAPTKMT2A | |
| SCHEMBL9761474 | 0.84 | THRA (0.49) | RARBTHRATHRBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |