Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.90 |
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.82 |
| ▸ | BLM | P54132 | 1/20 | 0.82 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799681 | 0.91 | MEN1 (0.79) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL32690121 | 0.90 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL18300094 | 0.90 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL9799705 | 0.88 | MEN1 (0.74) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL10943066 | 0.87 | KMT2A (0.94) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL16494872 | 0.87 | MEN1 (0.81) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL13698359 | 0.86 | MEN1 (0.91) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL1337428 | 0.86 | MEN1 (0.76) | MEN1KMT2AMAPTPOLBBLM | |
| SCHEMBL1572442 | 0.84 | MEN1 (0.76) | MEN1KMT2AMAPTPOLBSETD7 | |
| SCHEMBL31103641 | 0.84 | MEN1 (0.76) | MEN1KMT2AMAPTPOLBSETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277376-B1 | AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED | AKZO N.V. (NL) | 1991-02-27 | — | — | EP | disclosed |
| US-4980444-A | Polyamides, polyureas, polyimides; heat resistance, melt processability, high strength fibers, films | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |
| US-4851562-A | HEAT RESISTANCE, MELT PROCESS ABILITY | AKZO N.V. (NL) | 1989-07-25 | — | — | US | disclosed |
| EP-0277376-A1 | Aromatic amide groups-containing diamines and polymers in which these diamines are incorporated | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |