Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.62 |
| ▸ | DDX3X | O00571 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799650 | 0.91 | MEN1 (0.90) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9329754 | 0.90 | MEN1 (0.85) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL1337652 | 0.88 | MAPT (0.77) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL16494872 | 0.88 | MEN1 (0.81) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL8710919 | 0.87 | MEN1 (0.80) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL11572673 | 0.85 | MEN1 (0.76) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9800017 | 0.85 | GAA (0.77) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL6795867 | 0.84 | MEN1 (0.85) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL13698359 | 0.84 | MEN1 (0.91) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL11710023 | 0.84 | RAB9A (0.76) | MEN1KMT2AMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277376-B1 | AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED | AKZO N.V. (NL) | 1991-02-27 | — | — | EP | disclosed |
| US-4980444-A | Polyamides, polyureas, polyimides; heat resistance, melt processability, high strength fibers, films | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |
| US-4851562-A | HEAT RESISTANCE, MELT PROCESS ABILITY | AKZO N.V. (NL) | 1989-07-25 | — | — | US | disclosed |
| EP-0277376-A1 | Aromatic amide groups-containing diamines and polymers in which these diamines are incorporated | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |