Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799650 | 0.88 | MEN1 (0.90) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL16494872 | 0.88 | MEN1 (0.81) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL7872779 | 0.86 | KMT2A (0.81) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL8274340 | 0.86 | KMT2A (0.81) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL10395365 | 0.84 | MEN1 (0.60) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL12639153 | 0.83 | MEN1 (0.71) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL13465388 | 0.82 | MAPT (0.70) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL6014174 | 0.81 | RAB9A (0.71) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL8651293 | 0.81 | MEN1 (0.81) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL22251590 | 0.81 | MEN1 (0.71) | MEN1KMT2AALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277376-B1 | AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED | AKZO N.V. (NL) | 1991-02-27 | — | — | EP | disclosed |
| US-4980444-A | Polyamides, polyureas, polyimides; heat resistance, melt processability, high strength fibers, films | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |
| US-4851562-A | HEAT RESISTANCE, MELT PROCESS ABILITY | AKZO N.V. (NL) | 1989-07-25 | — | — | US | disclosed |
| EP-0277376-A1 | Aromatic amide groups-containing diamines and polymers in which these diamines are incorporated | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |