Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.55 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963012 | 1.00 | MAPT (0.62) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL9799652 | 1.00 | MAPT (0.62) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL29871432 | 0.85 | MAPT (0.64) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL1226009 | 0.85 | MAPT (0.64) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL1226012 | 0.85 | MAPT (0.64) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL6294475 | 0.83 | RAB9A (0.62) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL3209460 | 0.83 | RAB9A (0.62) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL3209446 | 0.83 | RAB9A (0.62) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL6294474 | 0.83 | RAB9A (0.62) | MAPTMAPK1NPC1RAB9ACYP2A6 | |
| SCHEMBL6070874 | 0.83 | MAPT (0.58) | MAPTMAPK1NPC1RAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255708-A | Polysubstituted carbazole derivative and synthesis method thereof | 重庆理工大学 | 2024-06-28 | — | — | CN | claimed |
| CN-118255708-A | Polysubstituted carbazole derivative and synthesis method thereof | 重庆理工大学 | 2024-06-28 | — | — | CN | disclosed |
| EP-0125059-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-02-27 | — | — | EP | disclosed |
| US-4664693-A | POSTEMERGENCE | ICI AUSTRALIA LIMITED (AU) | 1987-05-12 | — | — | US | disclosed |