Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799371 | 0.88 | SMN1; SMN2 (0.32) | HMGCR | |
| SCHEMBL10610743 | 0.82 | HMGCR (0.41) | HMGCR | |
| SCHEMBL10612687 | 0.82 | HMGCR (0.39) | HMGCR | |
| SCHEMBL9799735 | 0.81 | HMGCR (0.32) | HMGCR | |
| SCHEMBL10610197 | 0.79 | HMGCR (0.51) | HMGCR | |
| SCHEMBL9799374 | 0.79 | HMGCR (0.31) | HMGCR | |
| SCHEMBL9798947 | 0.77 | HMGCR (0.36) | HMGCR | |
| SCHEMBL10611077 | 0.74 | HMGCR (0.57) | HMGCR | |
| SCHEMBL10609448 | 0.74 | KCNN4 (0.33) | — | |
| SCHEMBL10437542 | 0.73 | HMGCR (0.45) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |