Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611800 | 0.82 | CES2 (0.36) | KCNN4SMN1; SMN2KMT2AATMALDH1A1 | |
| SCHEMBL10610722 | 0.78 | MGLL (0.36) | ELANESMN1; SMN2KMT2AATMALDH1A1 | |
| SCHEMBL9799727 | 0.74 | HMGCR (0.37) | — | |
| SCHEMBL9799371 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2KMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL16198654 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL10609456 | 0.72 | MEN1 (0.46) | KCNN4SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL27997589 | 0.72 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2AALDH1A1MAPTHSD17B10 | |
| SCHEMBL9726597 | 0.71 | ELANE (0.39) | ELANESMN1; SMN2KMT2AATMTDP1 | |
| SCHEMBL4675449 | 0.70 | POLB (0.40) | KCNN4SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL10611777 | 0.70 | MEN1 (0.33) | KCNN4KMT2AMEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |