Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799727 | 0.88 | HMGCR (0.37) | HMGCR | |
| SCHEMBL10609466 | 0.82 | HMGCR (0.34) | SMN1; SMN2HMGCRLTA4H | |
| SCHEMBL9799374 | 0.80 | HMGCR (0.31) | HMGCR | |
| SCHEMBL9726588 | 0.78 | HMGCR (0.40) | HMGCR | |
| SCHEMBL9799735 | 0.78 | HMGCR (0.32) | HMGCR | |
| SCHEMBL9726888 | 0.78 | HMGCR (0.42) | HMGCR | |
| SCHEMBL10610212 | 0.77 | LTA4H (0.33) | ALDH1A1HSD17B10LTA4H | |
| SCHEMBL10609349 | 0.74 | HMGCR (0.48) | SMN1; SMN2KMT2AALDH1A1HSD17B10HMGCR | |
| SCHEMBL10609448 | 0.74 | KCNN4 (0.33) | SMN1; SMN2KMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL10610197 | 0.70 | HMGCR (0.51) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |