Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378050 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL22439815 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AATMMEN1SMN1; SMN2 | |
| SCHEMBL601392 | 0.79 | ATM (0.46) | ALDH1A1KMT2AATMMEN1MAPT | |
| SCHEMBL601391 | 0.79 | ATM (0.46) | ALDH1A1KMT2AATMMEN1MAPT | |
| Hydrochloric Acid SCHEMBL11248291 | 0.77 | ATM (0.45) | ALDH1A1KMT2AATMMEN1MAPT | |
| SCHEMBL6671813 | 0.77 | NPSR1 (0.44) | ALDH1A1ATMMAPTSMN1; SMN2POLB | |
| SCHEMBL22726415 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ATMMAPTSMN1; SMN2LMNA | |
| SCHEMBL6671803 | 0.76 | TSPO (0.46) | ALDH1A1KMT2AATMMEN1MAPT | |
| SCHEMBL1304855 | 0.75 | STAT3 (0.45) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11248272 | 0.74 | HSD17B10 (0.44) | ALDH1A1KMT2AATMMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277376-B1 | AROMATIC AMIDE GROUPS-CONTAINING DIAMINES AND POLYMERS IN WHICH THESE DIAMINES ARE INCORPORATED | AKZO N.V. (NL) | 1991-02-27 | — | — | EP | disclosed |
| US-4980444-A | Polyamides, polyureas, polyimides; heat resistance, melt processability, high strength fibers, films | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |
| EP-0277376-A1 | Aromatic amide groups-containing diamines and polymers in which these diamines are incorporated | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |