Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800213 | 0.94 | CYP2C9 (0.48) | CYP2C9GAASMN1; SMN2HSD17B10POLB | |
| SCHEMBL9765559 | 0.94 | CYP2C9 (0.48) | CYP2C9GAASMN1; SMN2HSD17B10POLB | |
| SCHEMBL9765586 | 0.88 | KMT2A (0.39) | KMT2APOLBMRGPRX4LMNATDP1 | |
| SCHEMBL9765595 | 0.88 | KMT2A (0.39) | KMT2APOLBMRGPRX4LMNATDP1 | |
| SCHEMBL9799899 | 0.83 | PYGL (0.36) | CYP2C9KMT2APOLBMRGPRX4CASP3 | |
| SCHEMBL9799897 | 0.83 | POLB (0.38) | SMN1; SMN2KMT2APOLBMRGPRX4LMNA | |
| SCHEMBL9765570 | 0.81 | POLB (0.40) | GAAPOLBLMNATDP1PYGL | |
| SCHEMBL195323 | 0.81 | POLB (0.40) | GAAPOLBLMNATDP1PYGL | |
| SCHEMBL9765550 | 0.81 | POLB (0.40) | GAAPOLBLMNATDP1PYGL | |
| SCHEMBL9765574 | 0.81 | POLB (0.40) | GAAPOLBLMNATDP1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231619-B1 | 3-PHENOXY(OR PHENYLTHIO)CYCLOPENTANECARBONYLAMINO ACID ANALOGUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | claimed |