Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800484 | 0.85 | KMT2A (0.59) | TSHRHSD17B10MEN1KMT2ANPSR1 | |
| SCHEMBL8909660 | 0.84 | SRR (0.51) | HPGDTSHRGAAMEN1KMT2A | |
| SCHEMBL8682156 | 0.84 | SRR (0.51) | HPGDTSHRGAAMEN1KMT2A | |
| SCHEMBL9359097 | 0.84 | SRR (0.51) | HPGDTSHRGAAMEN1KMT2A | |
| SCHEMBL4002126 | 0.80 | TSHR (0.46) | HPGDTSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8681953 | 0.79 | MEN1 (0.49) | HPGDTSHRGAAMEN1KMT2A | |
| SCHEMBL9354940 | 0.79 | MEN1 (0.49) | HPGDTSHRGAAMEN1KMT2A | |
| SCHEMBL30826821 | 0.78 | GRIN2B (0.54) | HPGDTSHRGAAMEN1KMT2A | |
| SCHEMBL27630775 | 0.78 | HSD17B10 (0.75) | HPGDTSHRGAAHSD17B10CHRM1 | |
| SCHEMBL26802538 | 0.78 | HSD17B10 (0.75) | HPGDTSHRGAAHSD17B10CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |