Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800601 | 0.90 | REN (0.48) | RENP2RX1MMP1MMP2MMP3 | |
| SCHEMBL8910133 | 0.88 | REN (0.51) | RENP2RX1 | |
| Hydrochloric Acid SCHEMBL9800528 | 0.87 | REN (0.52) | RENP2RX1 | |
| SCHEMBL9800598 | 0.85 | REN (0.48) | RENP2RX1 | |
| SCHEMBL9800781 | 0.83 | REN (0.55) | RENP2RX1 | |
| SCHEMBL8909404 | 0.80 | REN (0.62) | RENP2RX1 | |
| SCHEMBL8909040 | 0.80 | REN (0.54) | RENP2RX1 | |
| SCHEMBL9800706 | 0.80 | REN (0.46) | REN | |
| SCHEMBL9800778 | 0.79 | REN (0.55) | RENP2RX1 | |
| Enalkiren SCHEMBL123107 | 0.79 | REN (0.62) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |