Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.58 |
| ▸ | REN | P00797 | 17/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800652 | 0.84 | P2RX1 (0.77) | P2RX1REN | |
| SCHEMBL8909814 | 0.83 | REN (0.55) | P2RX1REN | |
| SCHEMBL8910661 | 0.82 | P2RX1 (0.52) | P2RX1RENCNR1MAOB | |
| SCHEMBL9800460 | 0.82 | P2RX1 (0.52) | P2RX1RENCNR1MAOB | |
| SCHEMBL9800552 | 0.82 | P2RX1 (0.59) | P2RX1REN | |
| SCHEMBL8909404 | 0.81 | REN (0.62) | P2RX1REN | |
| SCHEMBL8909157 | 0.80 | REN (0.55) | P2RX1REN | |
| SCHEMBL9800511 | 0.80 | REN (0.55) | P2RX1REN | |
| SCHEMBL9800781 | 0.78 | REN (0.55) | P2RX1REN | |
| SCHEMBL7290665 | 0.78 | P2RX1 (0.46) | P2RX1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |