Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910628 | 0.92 | KMT2A (0.56) | KMT2AITGB3ITGA2B | |
| SCHEMBL10883284 | 0.89 | KMT2A (0.59) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL7044299 | 0.86 | ATM (0.67) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL7044293 | 0.86 | ATM (0.67) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL9716776 | 0.86 | ATM (0.67) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL9716778 | 0.86 | ATM (0.67) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL7039089 | 0.86 | ATM (0.67) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL9417356 | 0.86 | HDAC1 (0.56) | HDAC8 | |
| SCHEMBL9800497 | 0.85 | KMT2A (0.57) | KMT2AITGB3ITGA2BATMFPR2 | |
| SCHEMBL14684392 | 0.82 | HDAC8 (0.64) | ITGB3ITGA2BATMFPR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |