Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654138 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL11012641 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL9800655 | 0.83 | KMT2A (0.64) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL366012 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL3141283 | 0.83 | HTT (0.44) | ALDH1A1HDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL29612551 | 0.83 | PPARG (0.53) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL28730677 | 0.83 | PPARG (0.53) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL17164822 | 0.83 | NPC1 (0.61) | ALDH1A1MEN1KMT2AHTTMAPT | |
| Hydrochloric Acid SCHEMBL27777765 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL13548668 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |