Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28730677 | 0.85 | PPARG (0.53) | KMT2AMEN1KDM4EPKMALDH1A1 | |
| SCHEMBL29612551 | 0.85 | PPARG (0.53) | KMT2AMEN1KDM4EPKMALDH1A1 | |
| SCHEMBL1997355 | 0.84 | KMT2A (0.56) | KMT2AMEN1PDE7AKDM4EGAA | |
| SCHEMBL9800709 | 0.83 | ALDH1A1 (0.51) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL6725914 | 0.83 | PDE7A (0.66) | KMT2AMEN1PDE7AKDM4EGAA | |
| SCHEMBL3822283 | 0.82 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL10654138 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL366012 | 0.79 | ALDH1A1 (0.62) | KMT2AMEN1KDM4EGAAPKM | |
| SCHEMBL9800640 | 0.79 | MAPT (0.58) | KMT2AMEN1PDE7AKDM4EALDH1A1 | |
| SCHEMBL14021995 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2SCN9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |