Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094428 | 0.85 | KDM4E (0.48) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7028651 | 0.82 | MAPT (0.43) | MAPTRAB9AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9112617 | 0.77 | TSHR (0.45) | MAPTRAB9AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9112611 | 0.77 | TSHR (0.45) | MAPTRAB9AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6787246 | 0.77 | PKM (0.57) | MAPTRAB9AALDH1A1CYP1A2TDP1 | |
| SCHEMBL31441186 | 0.76 | ALDH1A1 (0.46) | MAPTRAB9AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29643004 | 0.76 | CYP1A2 (0.55) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2019522 | 0.76 | CYP1A2 (0.55) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15287099 | 0.75 | MEN1 (0.38) | MAPTRAB9AALDH1A1CYP1A2TDP1 | |
| SCHEMBL16507319 | 0.75 | MEN1 (0.38) | MAPTRAB9AALDH1A1CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3095159-A | — | — | None | — | — | JP | disclosed |
| JP-H0395159-A | 5-NITRO-2-SUBSTITUTED AMINOPYRIDINE DERIVATIVE AND ITS PRODUCTION | KOEI CHEM CO LTD | 1991-04-19 | — | — | JP | disclosed |