Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800840 | 0.94 | NPC1 (0.36) | NPC1RAB9AALDH1A1 | |
| SCHEMBL9800819 | 0.86 | MGLL (0.40) | RARBNPC1MGLLFAAHHSD17B10 | |
| SCHEMBL10418079 | 0.84 | SPHK1 (0.39) | — | |
| SCHEMBL10418078 | 0.84 | SPHK1 (0.39) | — | |
| SCHEMBL10418986 | 0.81 | SPHK1 (0.43) | THRATHRB | |
| SCHEMBL10418985 | 0.81 | SPHK1 (0.43) | THRATHRB | |
| SCHEMBL10418110 | 0.81 | SPHK1 (0.45) | HPGDALDH1A1THRATHRB | |
| SCHEMBL10416774 | 0.81 | SPHK1 (0.45) | HPGDALDH1A1THRATHRB | |
| SCHEMBL10416784 | 0.81 | SPHK1 (0.45) | HPGDALDH1A1THRATHRB | |
| SCHEMBL10416782 | 0.81 | SPHK1 (0.45) | HPGDALDH1A1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249081-B1 | TRANSHEXAHYDROTEREPHTALIC ACID ESTER DERIVATIVES | Sato, Hisato (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4946991-A | Liquid ccrystals or their additives | SATO HISATO (JP) | 1990-08-07 | — | — | US | disclosed |