Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.62 |
| ▸ | FAAH | O00519 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30349 | 1.00 | SLC6A5 (0.62) | SLC6A5FAAHMEN1TP53CYP1A2 | |
| SCHEMBL25711820 | 1.00 | SLC6A5 (0.62) | SLC6A5FAAHMEN1TP53CYP1A2 | |
| SCHEMBL769868 | 1.00 | SLC6A5 (0.62) | SLC6A5FAAHMEN1TP53CYP1A2 | |
| SCHEMBL31348788 | 1.00 | SLC6A5 (0.62) | SLC6A5FAAHMEN1TP53CYP1A2 | |
| SCHEMBL769870 | 1.00 | SLC6A5 (0.62) | SLC6A5FAAHMEN1TP53CYP1A2 | |
| SCHEMBL3096362 | 1.00 | SLC6A5 (0.62) | SLC6A5FAAHMEN1TP53CYP1A2 | |
| SCHEMBL6332840 | 0.95 | KDM4E (0.65) | SOAT1KDM4E | |
| SCHEMBL5146257 | 0.95 | KDM4E (0.65) | SOAT1KDM4E | |
| SCHEMBL29619662 | 0.95 | KDM4E (0.65) | SOAT1KDM4E | |
| SCHEMBL1702127 | 0.91 | EPHX2 (0.60) | SLC6A5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297610-B1 | N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | claimed |
| EP-0297610-B1 | N-[(2,6-disubstituted)phenyl]-urea and carbamate inhibitors of acyl-CoA:cholesterol acyl-transferase | WARNER-LAMBERT COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |